Dion R Brocks Selected Research

halofantrine (Halfan)

7/2012	Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes.
7/2009	The effect of experimental hyperlipidemia on the stereoselective tissue distribution, lipoprotein association and microsomal metabolism of (+/-)-halofantrine.
8/2002	The influence of lipids on stereoselective pharmacokinetics of halofantrine: Important implications in food-effect studies involving drugs that bind to lipoproteins.
1/2002	Stereoselective halofantrine and desbutylhalofantrine disposition in the rat: cardiac and plasma concentrations and plasma protein binding.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Dion R Brocks Research Topics

Disease

14	Hyperlipidemias (Hyperlipidemia) 03/2020 - 08/2002
6	Obesity 03/2020 - 12/2012
3	Neoplasms (Cancer) 01/2018 - 01/2006
2	Type 2 Diabetes Mellitus (MODY) 01/2017 - 07/2011
2	Hepatocellular Carcinoma (Hepatoma) 03/2016 - 05/2007
2	Hypoxia (Hypoxemia) 03/2013 - 01/2012
2	Renal Cell Carcinoma (Grawitz Tumor) 04/2012 - 09/2011
2	Cardiac Arrhythmias (Arrythmia) 01/2010 - 01/2002
2	Hyperlipoproteinemias 04/2007 - 10/2006
1	Insulin Resistance 01/2017
1	Community-Acquired Infections 09/2012
1	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2012
1	Brain Injuries (Brain Injury) 01/2012
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2012
1	Gout 09/2011
1	Exanthema (Rash) 09/2011
1	Pancreatitis 09/2011
1	Disease Progression 09/2011
1	Hyperuricemia 09/2011
1	Weight Gain 05/2008
1	Body Weight (Weight, Body) 05/2008
1	Mycoses (Diseases, Fungus) 05/2007
1	Acidosis 12/2002

Drug/Important Bio-Agent (IBA)

7	Amiodarone (Amiodarona)FDA LinkGeneric 11/2018 - 09/2005
6	Poloxamer (Poloxamer 407)IBA 05/2017 - 01/2006
5	Cyclosporine (Ciclosporin)FDA LinkGeneric 02/2014 - 10/2006
4	Ketoconazole (Nizoral)FDA LinkGeneric 03/2016 - 05/2007
4	halofantrine (Halfan)FDA Link 07/2012 - 01/2002
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2020 - 05/2007
3	Pharmaceutical PreparationsIBA 01/2013 - 11/2011
3	Lipoproteins (Lipoprotein)IBA 01/2013 - 10/2006
2	Dronedarone FDA Link 03/2020 - 09/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 05/2017 - 05/2007
2	Metformin (Glucophage)FDA LinkGeneric 05/2017 - 07/2011
2	Messenger RNA (mRNA)IBA 05/2017 - 05/2007
2	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 03/2016 - 05/2007
2	Everolimus FDA Link 04/2012 - 09/2011
2	TOR Serine-Threonine KinasesIBA 04/2012 - 09/2011
2	AzolesIBA 12/2007 - 05/2007
2	Itraconazole (Sporanox)FDA LinkGeneric 12/2007 - 05/2007
1	Protein Isoforms (Isoforms)IBA 01/2020
1	Lidocaine (Xylocaine)FDA LinkGeneric 01/2020
1	RadiopharmaceuticalsIBA 01/2018
1	fluoroazomycin arabinosideIBA 01/2018
1	guanidine carboxamideIBA 05/2017
1	CationsIBA 01/2017
1	FatsIBA 01/2017
1	Morphine (MS Contin)FDA LinkGeneric 01/2017
1	LeptinIBA 01/2017
1	CarbohydratesIBA 01/2017
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 03/2016
1	EnzymesIBA 03/2016
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 02/2014
1	AdipokinesIBA 01/2013
1	LipidsIBA 01/2013
1	Azithromycin (Zithromax)FDA LinkGeneric 09/2012
1	Blood Proteins (Serum Proteins)IBA 07/2012
1	Cytochrome P-450 CYP3AIBA 07/2012
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2012
1	Sunitinib (Sutent)FDA Link 04/2012
1	salicylhydroxamic acid (SHAM)IBA 01/2012
1	Free RadicalsIBA 01/2012
1	Oxygen (Dioxygen)IBA 01/2012
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2012
1	Midazolam (Versed)FDA LinkGeneric 11/2011
1	Lipase (Acid Lipase)FDA Link 09/2011
1	Tyrosine Kinase InhibitorsIBA 09/2011
1	Sorafenib (BAY 43-9006)FDA Link 09/2011
1	IsoenzymesIBA 09/2008
1	quinone (benzoquinone)IBA 12/2007
1	CarcinogensIBA 12/2007
1	Oxidoreductases (Dehydrogenase)IBA 12/2007
1	NAD (NADH)IBA 12/2007
1	Fluconazole (Zonal)FDA LinkGeneric 05/2007
1	Antifungal AgentsIBA 05/2007
1	desethylamiodaroneIBA 04/2007
1	Immunosuppressive Agents (Immunosuppressants)IBA 10/2006
1	Janus Kinase 2IBA 01/2006
1	cucurbitacin IIBA 01/2006
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2006
1	Lactic Acid (Lactate)FDA LinkGeneric 12/2002
1	Biological ProductsIBA 12/2002
1	AcidsIBA 12/2002
1	Antimalarials (Antimalarial Agents)IBA 01/2002

Therapy/Procedure

1	Gastric Bypass (Roux-en-Y Gastric Bypass) 12/2012
1	Resuscitation 01/2012
1	Intraperitoneal Injections 10/2006